| Identification | Back Directory | [Name]
Bosutinib Impurity 5 | [CAS]
1391063-17-4 | [Synonyms]
Bosutinib isomer 1
Bosutinib Isomer I
Bosutinib Isomer I (PF-06651481-00)
3-Quinolinecarbonitrile, 4-[(3,5-dichloro-4-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]- | [Molecular Formula]
C26H29Cl2N5O3 | [MDL Number]
MFCD22418831 | [MOL File]
1391063-17-4.mol | [Molecular Weight]
530.45 |
| Chemical Properties | Back Directory | [storage temp. ]
room temp | [solubility ]
Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly, Heated) | [form ]
Solid | [color ]
White to Light Brown | [Stability:]
Stable under recommended storage conditions., Stable Under Recommended Storage C |
| Hazard Information | Back Directory | [Uses]
Kinase inhibitors, such as?bosutinib,?are useful cancer drugs but their target specificity is not fully understood. 4-[(3,5-Dichloro-4-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrile has been employed as a clinical kinase inhibitor bosutinib to elucidate the recognition mechanism between the ATP-binding site and the compound. | [Biological Activity]
PF-06651481-00 is an isomer of orally available dual Src/Abl kinase inhibitor Bosutinib. |
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BOC Sciences
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16314854226 |
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www.bocsci.com |
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Roark Standards
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0755-83552066 15986688328 |
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roarkstandards.com |
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Energy Chemical
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021-58432009 400-005-6266 |
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http://www.energy-chemical.com |
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InvivoChem
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13549236410 |
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https://www.invivochem.cn/ |
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