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ChemicalBook--->CAS DataBase List--->1388841-50-6

1388841-50-6

1388841-50-6 Structure

1388841-50-6 Structure
IdentificationBack Directory
[Name]

KPT 251, >=98%
[CAS]

1388841-50-6
[Synonyms]

KPT251
AOB6639
KPT 251, >=98%
SCHEMBL11318201
SCHEMBL11318201; AOB6639;
2-[(Z)-2-{3-[3,5-Bis(trifluoromethyl)phenyl]-1H-1,2,4-triazol-1-yl}vinyl]-1,3,4-oxadiazole
[Molecular Formula]

C14H7F6N5O
[MDL Number]

MFCD28144513
[MOL File]

1388841-50-6.mol
[Molecular Weight]

375.23
Chemical PropertiesBack Directory
[Boiling point ]

417.9±55.0 °C(Predicted)
[density ]

1.58±0.1 g/cm3(Predicted)
[storage temp. ]

-20°C
[solubility ]

DMSO: 25mg/mL
[form ]

Solid
[pka]

-0.42±0.50(Predicted)
[color ]

Off-white to yellow
Hazard InformationBack Directory
[Uses]

KPT 251 is a novel CRM1 inhibitor, which has been shown to be effective in the treatment of acute myeloid leukemia.
[Biological Activity]

Cell permeable: yes''Primary Target
XPO1''Reversible: no
Spectrum DetailBack Directory
[Spectrum Detail]

KPT 251, >=98%(1388841-50-6)1HNMR
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