| Identification | Back Directory | [Name]
N-DESMETHYL IMATINIB | [CAS]
1356565-46-2 | [Synonyms]
N-DESMETHYL GLEEVEC
N-DESMETHYL IMATINIB
Imatinib Impurity 53
N-DESMETHYL IMATINIB USP/EP/BP
N-DESMETHYL IMATINIB impurity B
Imatinib desmethyl (as formate)
N-4-((4-Methylpiperazin-1-yl)methyl)benzaldehyde
Benzamide, N-[2-methyl-5-[[4-[(4-methyl-1-piperazinyl)methyl]benzoyl]amino]phenyl]-4-[(4-methyl-1-piperazinyl)methyl]-N-[4-(3-pyridinyl)-2-pyrimidinyl]- | [Molecular Formula]
C42H47N9O2 | [MDL Number]
MFCD07369291 | [MOL File]
1356565-46-2.mol | [Molecular Weight]
709.88 |
| Chemical Properties | Back Directory | [Melting point ]
180 - 190°C | [density ]
1.248±0.06 g/cm3(Predicted) | [storage temp. ]
-20°C Freezer | [solubility ]
Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
13.20±0.70(Predicted) | [color ]
Off-White to Light Yellow |
| Hazard Information | Back Directory | [Uses]
Gleevec N-4-((4-Methylpiperazin-1-yl)methyl)benzaldehyde is an impurity of Gleevec (G407000), a tyrosine kinase inhibitor which is highly specific for BCR-ABL, the enzyme associated with chronic myelogenous leukemia (CML) and certain forms of acute lymphoblastic leukemia (ALL). | [Uses]
N-Desmethyl Imatinib (Imatinib EP Impurity C) is a metabolite of Gleevec, a tyrosine kinase inhibitor which is highly specific for BCR-ABL, the enzyme associated with chronic myelogenous leukemia (CML) and certain forms of acute lymphoblastic leukemia (ALL). It is a COVID19-related research product. |
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