| Identification | Back Directory | [Name]
VALNEMULIN HYDROCHLORIDE | [CAS]
133868-46-9 | [Synonyms]
econor
Etodoiac
VALNEMULIN HCL
ValneMulin hyd
VALNEMULIN HYDROCH
Valnemulin Hydrochlorid
VALNEMULIN HYDROCHLORIDE
Valnemulin HCl 50% premix
Valnemulin hydrochloride CRS
Valnemulin Hydrochloride, ?>99.0%
VALNEMULIN HYDROCHLORIDE USP/EP/BP
Valnemulin hydrochloride Solution, 100ppm
(3aR,5R,7S,8S,9R,12R)-8-Hydroxy-4,7,9,12-tetramethyl-3-oxo-7-vinyldecahydro-4,9a-propanocyclopenta[8]annulen-5-yl 2-((1-((R)-2-amino-3-methylbutanamido)-2-methylpropan-2-yl)thio)acetate hydrochloride
Acetic acid,[[2-[[(2R)-2-aMino-3-Methyl-1-oxobutyl]aMino]-1,1-diMethylethyl]thio]-,(3aS,4R,5S,6S,8R,9R,9aR,10R)-6-ethenyldecahydro-5-hydroxy-4,6,9,10-tetraMethyl-1-oxo-3a,9-propano-3aH-cyclopentacycloocten-8-ylester, Monohydrochloride (9CI)
Acetic acid, 2-[[2-[[(2R)-2-amino-3-methyl-1-oxobutyl]amino]-1,1-dimethylethyl]thio]-, (3aS,4R,5S,6S,8R,9R,9aR,10R)-6-ethenyldecahydro-5-hydroxy-4,6,9,10-tetramethyl-1-oxo-3a,9-propano-3aH-cyclopentacycloocten-8-yl ester, hydrochloride (1:1) | [EINECS(EC#)]
685-606-9 | [Molecular Formula]
C31H53ClN2O5S | [MDL Number]
MFCD08458958 | [MOL File]
133868-46-9.mol | [Molecular Weight]
601.28 |
| Chemical Properties | Back Directory | [Melting point ]
140-143?C | [storage temp. ]
0-6°C | [solubility ]
DMSO (Slightly), Ethanol (Slightly), Methanol (Slightly) | [form ]
neat | [color ]
White to Off-White | [Merck ]
14,9911 | [InChIKey]
MFBPRQKHDIVLOJ-AFFLPQGKSA-N |
| Hazard Information | Back Directory | [Chemical Properties]
White to Off-White Solid | [Uses]
Hydrochloride salt Valnemulin, semisynthetic antibiotic; derivative of pleuromutilin. Antibacterial. | [Uses]
Valnemulin hydrochloride is the salt prepared from valnemulin taking advantage of the basic amino group which protonates and readily forms the salt in hydrochloric acid solutions. The hydrochloride is the preferred formulation for pharmaceutical applications. Valnemulin is a broad spectrum antibiotic used to control gastrointestinal infections in animals, and shows no cross resistance to other antibiotic classes. Like all the pleuromutilins, valnemulin inhibits protein synthesis by binding to domain V of 23S RNA. | [Biological Activity]
Valnemulin Hydrochloride inhibits bacterial protein synthesis by binding to the 50S subunit of the bacterial ribosome. More specificallyit binds to the peptidyl transferase center of the ribosome and interferes with the transfer of amino acids to growing polypeptide chainsleading to the inhibition of protein synthesis and bacterial death. | [storage]
Store at -20°C |
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