| Identification | Back Directory | [Name]
PF-5190457 | [CAS]
1334782-79-4 | [Synonyms]
PF-5190457
PF-05190457
PF-05190457 >=95% (HPLC)
1-[2-[(1R)-2,3-Dihydro-5-(6-methyl-4-pyrimidinyl)-1H-inden-1-yl]-2,7-diazaspiro[3,5]non-7-yl]-2-(2-methylimidazo[2,1-b]thiazol-6-yl)ethanone | [Molecular Formula]
C29H32N6OS | [MOL File]
1334782-79-4.mol | [Molecular Weight]
512.67 |
| Chemical Properties | Back Directory | [density ]
1.41±0.1 g/cm3(Predicted) | [storage temp. ]
room temp | [solubility ]
DMSO: 250 mg/mL (487.64 mM) | [form ]
powder | [pka]
8.38±0.20(Predicted) | [color ]
white to beige | [optical activity]
[α]/D +45 to +55°, c = 0.5 in methanol |
| Hazard Information | Back Directory | [Uses]
PF 5190457 is a potent, selective, and orally bioavailable ghrelin receptor inverse agonist. | [Biochem/physiol Actions]
PF-05190457 is an orally available, potent and selective ghrelin receptor inverse agonist. PF-05190457 potently increases insulin secretion in glucose-stimulated human islets. | [storage]
Store at -20°C |
|
| Company Name: |
Sigma-Aldrich
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021-61415566 800-8193336 |
| Website: |
https://www.sigmaaldrich.cn |
| Company Name: |
DC Chemicals
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021-58447131 13564518121 |
| Website: |
http://m.approvedhomemanagement.com/ShowSupplierProductsList927327/0.htm |
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