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ChemicalBook--->CAS DataBase List--->1334493-07-0

1334493-07-0

1334493-07-0 Structure

1334493-07-0 Structure
IdentificationBack Directory
[Name]

BP-1-102
[CAS]

1334493-07-0
[Synonyms]

BP-1-102
STAT3 Inhibitor XVIII
BP-1-102; BP1-102; BP 1-102.
STAT3 Inhibitor XVIII, BP-1-102
STAT3 INHIBITOR XVIII;BP1-102;BP 1-102
4-(N-(4-Cyclohexylbenzyl)-2-(2,3,4,5,6-pentafluoro-N-methylphenylsulfonamido)acetamido)-2-hydr
4-(N-(4-cyclohexylbenzyl)-2-(2,3,4,5,6-pentafluoro-N-methylphenylsulfonamido)acetamido)-2-hydroxybenzoic acid
Benzoic acid, 4-[[(4-cyclohexylphenyl)methyl][2-[methyl[(2,3,4,5,6-pentafluorophenyl)sulfonyl]amino]acetyl]amino]-2-hydroxy-
[Molecular Formula]

C29H27F5N2O6S
[MDL Number]

MFCD29477477
[MOL File]

1334493-07-0.mol
[Molecular Weight]

626.59
Chemical PropertiesBack Directory
[Boiling point ]

749.2±70.0 °C(Predicted)
[density ]

1.474±0.06 g/cm3(Predicted)
[storage temp. ]

Inert atmosphere,Store in freezer, under -20°C
[solubility ]

DMSO:15.0(Max Conc. mg/mL);23.9(Max Conc. mM)
[form ]

A crystalline solid
[pka]

3.15±0.10(Predicted)
[color ]

White to off-white
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H302+H312+H332-H315-H319
[Precautionary statements ]

P501-P261-P270-P271-P264-P280-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330-P302+P352+P312-P304+P340+P312
Hazard InformationBack Directory
[Uses]

BP-1-102 is a potent and selective STAT3 inhibitor. STAT3 is a cytoplasmic transcription factor that induces the expression of genes related to tumorigenesis. BP 1-102 exhibits antitumor activity against Waldenstrom macroglobulinemia, a rare form of B cell non-Hodgkin lymphoma.
[Biological Activity]

Primary Target
Stat3
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