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ChemicalBook--->CAS DataBase List--->1332391-04-4

1332391-04-4

1332391-04-4 Structure

1332391-04-4 Structure
IdentificationBack Directory
[Name]

Apalutamide Acid Impurity
[CAS]

1332391-04-4
[Synonyms]

Apalutamide-COOH
Apalutamide Acid Impurity
[Molecular Formula]

C20H12F4N4O3S
[MDL Number]

MFCD33023514
[MOL File]

1332391-04-4.mol
[Molecular Weight]

464.39
Chemical PropertiesBack Directory
[Boiling point ]

661.7±65.0 °C(Predicted)
[density ]

1.69±0.1 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[form ]

Solid
[pka]

2.81±0.10(Predicted)
[color ]

White to off-white
Hazard InformationBack Directory
[Uses]

Apalutamide-COOH is a metabolite of Apalutamide. Apalutamide is a potent and competitive androgen receptor (AR) antagonist, binding AR with an IC50 of 16 nM[1].
[storage]

Store at -20°C
[References]

[1] Nicholas D. Smith, et al. Androgen receptor modulators and uses thereof. WO2011103202A2.
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