| Identification | Back Directory | [Name]
L 687908 | [CAS]
132565-33-4 | [Synonyms]
908
L 687908
(2S)-N-[(1H-Benzimidazol-2-yl)methyl]-2-[[(2R,4S,5S)-5-(tert-butyloxycarbonylamino)-4-hydroxy-6-phenyl-2-[(E)-3-phenyl-2-propenyl]hexanoyl]amino]-3-methylvaleramide
Carbamic acid, N-[(1S,2S,4R,6E)-4-[[[(1S,2S)-1-[[(1H-benzimidazol-2-ylmethyl)amino]carbonyl]-2-methylbutyl]amino]carbonyl]-2-hydroxy-7-phenyl-1-(phenylmethyl)-6-hepten-1-yl]-, 1,1-dimethylethyl ester | [Molecular Formula]
C40H51N5O5 | [MDL Number]
MFCD00902827 | [MOL File]
132565-33-4.mol | [Molecular Weight]
681.86 |
| Hazard Information | Back Directory | [Description]
L 687908 is a potent hydroxyethylene-containing HIV protease inhibitor. | [Uses]
L-687908 is a HIV-1 protease inhibitor (CIC95: 12 nM)[1][2]. | [References]
[1] Kohl NE, et al. Expression of active human immunodeficiency virus type 1 protease by noninfectious chimeric virus particles. J Virol. 1991 Jun;65(6):3007-14. DOI:10.1128/JVI.65.6.3007-3014.1991
[2] Lin JH. Role of pharmacokinetics in the discovery and development of indinavir. Adv Drug Deliv Rev. 1999 Oct 18;39(1-3):33-49. DOI:10.1016/s0169-409x(99)00018-6 |
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