Identification | Back Directory | [Name]
CATPB | [CAS]
1322598-09-3 | [Synonyms]
CATPB CATPB >=98% (HPLC) (S)-3-(2-(3-Chlorophenyl)acetamido)-4-(4-(trifluoromethyl)phenyl)butanoic acid Benzenebutanoic acid, β-[[2-(3-chlorophenyl)acetyl]amino]-4-(trifluoromethyl)-, (βS)- | [Molecular Formula]
C19H17ClF3NO3 | [MDL Number]
MFCD30474718 | [MOL File]
1322598-09-3.mol | [Molecular Weight]
399.79 |
Chemical Properties | Back Directory | [Boiling point ]
579.3±50.0 °C(Predicted) | [density ]
1.353±0.06 g/cm3(Predicted) | [storage temp. ]
2-8°C | [solubility ]
Soluble in DMSO | [form ]
powder | [pka]
4.24±0.10(Predicted) | [color ]
white to beige |
Hazard Information | Back Directory | [Uses]
CATPB (cas# 1322598-09-3) is a useful research chemical.CATPB was used to prepare fluorescent tracer for the free fatty acid receptor 2 (FFA2/GPR43). | [Biological Activity]
CATPB is an acetamidophenylbutanoate derivative with inverse agonist and antagonist activity against humanbut not mouse or ratFFA2 (GPR43). CATPB inhibits both constitutive and propionate (C3) -stimulated hFFA2 GTPγS incorporation (IC50 ~35 and 320 nMrespectively; [C3] = EC80~125 nM)as well as C3-induced hFFA2 G159E activity (IC50 ~400 nM). CATPB is shown to inhibit C3-induced intracellular ERK phosphorylation in hFFA2-expressing cells (IC50 ~3 μM against 10 mM C3). | [storage]
Store at -20°C |
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Company Name: |
BOC Sciences
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Tel: |
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Website: |
https://www.bocsci.com |
Company Name: |
Energy Chemical
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Tel: |
021-58432009 400-005-6266 |
Website: |
http://www.energy-chemical.com |
Company Name: |
R&D Systems, Inc
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Tel: |
18003437475 18003437475 |
Website: |
www.rndsystems.com |
Company Name: |
Merck KGaA
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Tel: |
21-20338288 |
Website: |
www.sigmaaldrich.cn |
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