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ChemicalBook--->CAS DataBase List--->132036-88-5

132036-88-5

132036-88-5 Structure

132036-88-5 Structure
IdentificationBack Directory
[Name]

RAMOSETRON
[CAS]

132036-88-5
[Synonyms]

Nasea
Ibsetron
Nor-YM 060
RAMOSETRON
Unii-7zro0sc54y
Ramosetron [inn]
(-)-(R)-1-Methylindol-3-yl 4,5,6,7-tetrahydro-5-benzimidazolylketone
(1-methyl-3-indolyl)-[(5R)-4,5,6,7-tetrahydro-3H-benzimidazol-5-yl]methanone
(R)-5α-[(1-Methyl-1H-indol-3-yl)carbonyl]-4,5,6,7-tetrahydro-1H-benzimidazole
(R)-5-[(1-METHYLINDOLE-3-YL)CARBONYL]-4,5,6,7-TETRAHYDRO-1H-BEZIMIDAZOLE, 98+%
(5R)-5α-[(1-Methyl-1H-indole-3-yl)carbonyl]-4,5,6,7-tetrahydro-1H-benzimidazole
(1-Methyl-1H-indol-3-yl)[[(5R)-4,5,6,7-tetrahydro-1H-benzimidazol]-5α-yl] ketone
(R)-(1-Methyl-1H-indol-3-yl)(4,5,6,7-tetrahydro-1H-benzo[d]imidazol-6-yl)methanone
Methanone, (1-methyl-1H-indol-3-yl)[(6R)-4,5,6,7-tetrahydro-1H-benzimidazol-6-yl]-
Methanone, (1-methyl-1H-indol-3-yl)(4,5,6,7-tetrahydro-1H-benzimidazol-5-yl)-, (R)-
Methanone, (1-methyl-1H-indol-3-yl)[(5R)-4,5,6,7-tetrahydro-1H-benzimidazol-5-yl]- (9CI)
[Molecular Formula]

C17H17N3O
[MDL Number]

MFCD00868551
[MOL File]

132036-88-5.mol
[Molecular Weight]

279.34
Chemical PropertiesBack Directory
[alpha ]

D20 -16.5° (c 1.13 in methanol)
[Boiling point ]

579.7±50.0 °C(Predicted)
[density ]

1.33±0.1 g/cm3(Predicted)
[pka]

14.53±0.40(Predicted)
Hazard InformationBack Directory
[Uses]

Ramosetron is a serotonin 5HT3 receptor antagonist.
[Definition]

ChEBI: Ramosetron is a member of indoles.
[in vivo]

Ramosetron (0.01-0.1 mg/kg, p.o., twice daily for 5 days) Ameliorates 5-fluorouracil (5-FU) (HY-90006)-induced intestinal mucositis in C57BL/6 mice[2].

[IC 50]

5-HT3 Receptor
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