| Identification | Back Directory | [Name]
ARGIPRESSIN ACETATE | [CAS]
129979-57-3 | [Synonyms]
AVP
AC-AVP
AC[ARG8]VASOPRESSIN
ARGIPRESSIN ACETATE
Argipressine acetate
[Arg8]Vasopressin TFA
Acetate fine vasopressin
[Arg8]Vasopressin acetate
[8-ARG]VASOPRESSIN ACETATE
BETA-HYPOPHAMINE ACETATE SALT
Argipressine acetate USP/EP/BP
[8-ARGININE]VASOPRESSIN ACETATE
[ARG8]-VASOPRESSIN ACETATE SALT
ANTIDIURETIC HORMONE ACETATE SALT
ARGININE VASOPRESSIN ACETATE SALT
Argipressin Acetate, (Arg9)-Vasopressin
AC-CYS-TYR-PHE-GLN-ASN-CYS-PRO-ARG-GLY-NH2
CYS-TYR-PHE-GLN-ASN-CYS-PRO-ARG-GLY-NH2 ACETATE SALT
(CYS-TYR-PHE-GLN-ASN-CYS)CYCL-PRO-ARG-GLY-NH2 ACETATE SALT
[8-Arginine]Vasopressin acetate, Argipressin acetate, AVP | [Molecular Formula]
C48H69N15O14S2 | [MDL Number]
MFCD00133939 | [MOL File]
129979-57-3.mol | [Molecular Weight]
1144.28 |
| Chemical Properties | Back Directory | [Melting point ]
189 °C(dec.) | [storage temp. ]
−20°C
| [solubility ]
Water: 1 mg/ml | [form ]
powder to crystal | [color ]
White to Light yellow | [Water Solubility ]
Water: 1 mg/ml |
| Hazard Information | Back Directory | [Description]
Argipressin is a peptide hormone with vasoconstrictive and antidiuretic activities that binds to the vascular arginine vasopressin receptor, V1, with Kd values of 1.31 and 1.44 nM in A7r5 rat aortic smooth muscle cells and neonatal rat cardiomyocytes, respectively. It also stimulates the intracellular release of calcium in A7r5 cells (EC50 = 5 nM). In rat models, argipressin induces hypertension and tachycardia when injected into the lateral septal nuclei at a dose of 100-400 ng and increases heart rate and mean arterial pressure (MAP) when injected into the medial amygdaloid body at a dose of 150-600 ng. | [storage]
-20°C |
|
|