| Identification | Back Directory | [Name]
HIV (GP120) FRAGMENT (421-438) | [CAS]
129318-38-3 | [Synonyms]
gp120 fragment 421-438
HIV (GP120) FRAGMENT (421-438)
HIV ENVELOPE PROTEIN (GP120) FRAGMENT 421-438
HIV (gp120) Fragment (421-438) trifluoroacetate salt
LYS-GLN-PHE-ILE-ASN-MET-TRP-GLN-GLU-VAL-GLY-LYS-ALA-MET-TYR-ALA-PRO-PRO
H-LYS-GLN-PHE-ILE-ASN-MET-TRP-GLN-GLU-VAL-GLY-LYS-ALA-MET-TYR-ALA-PRO-PRO-OH
L-Lysyl-L-glutaminyl-L-phenylalanyl-L-isoleucyl-L-asparaginyl-L-methionyl-L-tryptophyl-L-glutaminyl-L-α-glutamyl-L-valylglycyl-L-lysyl-L-alanyl-L-methionyl-L-tyrosyl-L-alanyl-L-prolyl-L-proline
L-Proline, L-lysyl-L-glutaminyl-L-phenylalanyl-L-isoleucyl-L-asparaginyl-L-methionyl-L-tryptophyl-L-glutaminyl-L-α-glutamyl-L-valylglycyl-L-lysyl-L-alanyl-L-methionyl-L-tyrosyl-L-alanyl-L-prolyl- | [Molecular Formula]
C99H148N24O25S2 | [MDL Number]
MFCD00237103 | [MOL File]
129318-38-3.mol | [Molecular Weight]
2138.51 |
| Hazard Information | Back Directory | [Uses]
HIV gp120 421-438 is HIV antigen fragments, that conjugates with keyhole limpet hemocyanin (KLH) and generates specific anti-HIV antibody[1]. | [in vivo]
HIV gp120 421-438 (1 μmol, i.m., single dose) induces immune response in egg yolks from layer hens, conjugated with keyhole limpet hemocyanin (KLH)[1]. | Animal Model: | Vaccinated layer hens[1] | | Dosage: | 1 μmol | | Administration: | i.m., single dose | | Result: | Produced more titre of specific antibodies in the egg yolk of immunized chickens. |
| [References]
[1] Justiz-Vaillant A, et al., In vivo administration of anti-HIV hyper-immune eggs induces anti-anti-idiotypic antibodies against HIV gp120 peptides (fragments 308-331 and 421-438) and against HIV gp41 peptide (fragment 579-601) which have demonstrable protective capacity[J]. bioRxiv, 2021: 2021.05. 02.442298. |
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