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ChemicalBook--->CAS DataBase List--->12707-58-3

12707-58-3

12707-58-3 Structure

12707-58-3 Structure
IdentificationBack Directory
[Name]

GANGLIOSIDE GD1A DISODIUM SALT
[CAS]

12707-58-3
[Synonyms]

GD1A
GD1A 2NA
Ganglioside B1
Ganglioside GII
GD1A-GANGLIOSIDE
GANGLIOSIDE GD1A
disialogangloside GD1a
DISIALOGANGLIOSIDE GD1A
DISIALOGANGLIOSIDE GDIA
GD1a-Ganglioside sodium
DISALOGANGLIOSIDE GD1A 2NA
DISIALOGANGLIOSIDE GD1A 2NA
IV3NEUAC, II3NEUAC-GGOSE4CER
Disialoganglioside GD1a ,95%
GANGLIOSIDE GD1A DISODIUM SALT
Ganglioside GD1a (sodium salt)
DISIALOGANGLIOSIDE GD1A, BOVINE
Ganglioside GD1a (Porcine Brain)
GAL(SA)-GALNAC-GAL(SA)-GLC-CERAMIDE
DISIALOGANGLIOSIDE GD1A (NH4+ SALT)
Ganglioside GD1a mixture (sodium salt)
MONOSIALOGANGLIOSIDE GD1A DISODIUM SALT
GANGLIOSIDEGD1ADISODIUMSALT,BOVINEBRAIN
GANGLIOSIDE GD1A DISODIUM SALT USP/EP/BP
disialoganglioside-gd1A from bovine*brain
disialoganglioside G(D1A) from bovine brain
ganglioside gd1a, disialo from bovine brain
DISIALOGANGLIOSIDE-GD1A CELL CULTURE*TES TED
Ganglioside GD1a Mixture (bovine) (ammonium salt)
Ganglioside GD1a Mixture (porcine) (ammonium salt)
GANGLIOSIDEGD1ADISODIUMSALT,BOVINEBRAIN,CELLCULTUREGRADE
Disialoganglioside GD1a from bovine brain,Ganglioside GD1a, disialo from bovine brain
[Molecular Formula]

C84H146N4Na2O39
[MDL Number]

MFCD00130960
[MOL File]

12707-58-3.mol
[Molecular Weight]

1882.04
Chemical PropertiesBack Directory
[storage temp. ]

-20°C
[solubility ]

DMSO: soluble
[form ]

lyophilized powder
[BRN ]

6228822
Safety DataBack Directory
[Safety Statements ]

22-24/25
[WGK Germany ]

3
[F ]

10-21
[HS Code ]

29400090
Hazard InformationBack Directory
[Description]

Ganglioside GD1a is a sialic acid-containing glycosphingolipid found in brain, erythrocytes, bone marrow, testis, spleen, and liver. It can be shed from the surface of tumor cells into the microenvironment where it influences tumor-host cell interactions to promote tumor cell proliferation, invasion, and metastasis. Ganglioside GD1a (20 μM) also increases endothelial cell proliferation. Furthermore, ganglioside GD1a has been shown to act as a functional coreceptor for toll-like receptor 2 (TLR2), enabling the recruitment of TLR2 to lipid rafts when bound by a bacterial toxin. Ganglioside GD1a mixture contains ganglioside GD1a molecular species with C18:1 and C20:1 sphingoid backbones.
[Chemical Properties]

White powder
[Uses]

Ganglioside GD1a Disodium Salt is an agent with a stimulatory effect on phagocytosis and phagosome-lysosome.
[General Description]

Ganglioside GD1a is an anionic brain ganglioside. It is localized in the inner and outer membrane of nuclear envelope of the neuronal cells. GD1a contains a neutral tetrasaccharide core, with one or two sialic acid on the internal galactose. It also has an additional sialic acid on the non-reducing terminal of galactose.
[storage]

Store at -20°C
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