1261728-71-5

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1261728-71-5 Structure

Identification	Back Directory
[Name] 7-(Difluoromethyl)Quinoline
[CAS] 1261728-71-5
[Synonyms] 7-(Difluoromethyl)Quinoline Quinoline, 7-(difluoromethyl)- 7-(Difluoromethyl)Quinoline(WXC01613)
[Molecular Formula] C10H7F2N
[MDL Number] MFCD18416340
[MOL File] 1261728-71-5.mol
[Molecular Weight] 179.17

Safety Data	Back Directory
[Symbol(GHS) ] GHS07
[Signal word ] Warning
[Hazard statements ] H302-H315-H319-H335
[Precautionary statements ] P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P330-P332+P313-P337+P313-P362-P403+P233-P405-P501

Hazard Information	Back Directory
[Uses] 7-(Difluoromethyl)quinoline is an intermediate in the synthesis of GNE-781 (D447825), a derivative of a highly advanced, potent and selective bromodomain inhibitor of cyclic adenosine monophosphate response element binding protein (CBP). Inhibition of the bromodomain of the transcriptional regulator CBP/P300 is an especially interesting new therapeutic approach in oncology.
[Application] 7-(Difluoromethyl)Quinoline can be used as organic synthesis intermediate and pharmaceutical intermediate, mainly used in laboratory research and development process and chemical production process.

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