| Identification | Back Directory | [Name]
Ferulic acid-1,2,3-13C3
| [CAS]
1261170-81-3 | [Synonyms]
Ferulic acid-1,2,3-13C3
Ferulic acid-1,2,3-13C3 99 atom % 13C, 98% (CP) | [Molecular Formula]
C10H10O4 | [MOL File]
1261170-81-3.mol | [Molecular Weight]
197.211 |
| Hazard Information | Back Directory | [Uses]
Ferulic acid-13C3 is the 13C-labeled Ferulic acid. Ferulic acid is a novel fibroblast growth factor receptor 1 (FGFR1) inhibitor with IC50s of 3.78 and 12.5 μM for FGFR1 and FGFR2, respectively. | [Definition]
ChEBI:3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acid is a hydroxycinnamic acid. | [References]
[1] Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. DOI:10.1177/1060028018797110
[2] Yang GW, et al. Ferulic Acid Exerts Anti-Angiogenic and Anti-Tumor Activity by Targeting Fibroblast Growth Factor Receptor 1-Mediated Angiogenesis. Int J Mol Sci. 2015 Oct 12;16(10):24011-31. DOI:10.3390/ijms161024011
[3] Zeni AL, et al. Ferulic acid exerts antidepressant-like effect in the tail suspension test in mice: evidence for the involvement of the serotonergic system. Eur J Pharmacol. 2012 Mar 15;679(1-3):68-74. DOI:10.1016/j.ejphar.2011.12.041 |
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