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ChemicalBook--->CAS DataBase List--->125515-31-3

125515-31-3

125515-31-3 Structure

125515-31-3 Structure
IdentificationBack Directory
[Name]

N4-Benzoyl-7'-OH-N-trityl Morpholino cytosine
[CAS]

125515-31-3
[Synonyms]

PMO-C Precusor
N4-Benzoyl-7'-OH-N-trityl Morpholino cytosine
N4-Benzoyl-7'-hydroxymorpholino cytidine monomer
N4-Benzoyl-7'-hydroxy-N-trityl-morpholino cytosine monomer
N-(1-(6-(hydroxymethyl)-4-tritylmorpholin-2-yl)-2-oxo-1, 2-dihydropyrimidin-4-yl)benzamide
N-{1-[(2R,6)-6-(hydroxymethyl)-4tritylmorpholin-2-yl]-2-oxo-1,2-dihydropyrimidin-4-yl}benzamide
N-[1-[(2R,6S)-6-(Hydroxymethyl)-4-tritylmorpholin-2-yl]-2-oxo-1,2-dihydropyrimidine-4-yl]benzamide
Benzamide, N-[1,2-dihydro-1-[(2R,6S)-6-(hydroxymethyl)-4-(triphenylmethyl)-2-morpholinyl]-2-oxo-4-pyrimidinyl]-
[Molecular Formula]

C35H32N4O4
[MDL Number]

MFCD22666302
[MOL File]

125515-31-3.mol
[Molecular Weight]

572.65
Chemical PropertiesBack Directory
[density ]

1.24±0.1 g/cm3(Predicted)
[pka]

8.65±0.20(Predicted)
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H312-H332
[Precautionary statements ]

P264-P270-P301+P312-P330-P501-P261-P271-P304+P340-P312-P280-P302+P352-P312-P322-P363-P501
Hazard InformationBack Directory
[Uses]

N4-Benzoyl-7’-OH-N-trityl morpholino cytosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
[References]

[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005
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