| Identification | Back Directory | [Name]
N-(4-Fluorophenyl)-6-morpholino-9H-purin-2-amine | [CAS]
1251578-67-2 | [Synonyms]
Topoisomerase
N-(4-Fluorophenyl)-6-morpholino-9H-purin-2-amine
9H-Purin-2-amine, N-(4-fluorophenyl)-6-(4-morpholinyl)- | [Molecular Formula]
C15H15FN6O | [MDL Number]
MFCD22608428 | [MOL File]
1251578-67-2.mol | [Molecular Weight]
314.32 |
| Hazard Information | Back Directory | [Uses]
Topoisomerase IIα-IN-8 (compound 15) is a weak human DNA topoisomerase IIa (htIIa) inhibitor, with an IC50 of 462 ± 38.0 μM[1]. | [IC 50]
topoisomerase II alpha | [References]
[1] Barbara Pogorel?nik, et al. Discovery of Mono- and Disubstituted 1H-Pyrazolo[3,4]pyrimidines and 9H-Purines as Catalytic Inhibitors of Human DNA Topoisomerase?II. ChemMedChem, 2015. |
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