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ChemicalBook--->CAS DataBase List--->1245157-42-9

1245157-42-9

1245157-42-9 Structure

1245157-42-9 Structure
IdentificationBack Directory
[Name]

2-[[6-[4-(2-Hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidinyl]amino]-5-thiazolecarboxylic acid
[CAS]

1245157-42-9
[Synonyms]

2-[[6-[4-(2-Hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidinyl]amino]-5-thiazolecarboxylic acid
5-Thiazolecarboxylic acid, 2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidinyl]amino]-
2-({6-[4-(2-Hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidinyl}amino)-1,3-thiazole-5-carboxylic acid
2-((6-(4-(2-Hydroxyethyl)piperazin-1-yl)-2-methylpyrimidin-4-yl)amino)thiazole-5-carboxylic acid (Dasatinib Impurity)
[Molecular Formula]

C15H20N6O3S
[MOL File]

1245157-42-9.mol
[Molecular Weight]

364.42
Chemical PropertiesBack Directory
[Boiling point ]

638.2±65.0 °C(Predicted)
[density ]

1.447±0.06 g/cm3(Predicted)
[pka]

2?+-.0.10(Predicted)
Hazard InformationBack Directory
[Uses]

2-[[6-[4-(2-Hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidinyl]amino]-5-thiazolecarboxylic acid is an intermediate in the preparation of Dasatinib (D193600), a new, oral, small-molecule Tyrosine Kinase Inhibitor (TKI) for the treatment of CML. Antineoplastic.
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