| Identification | Back Directory | [Name]
1-((TRIMETHYLSILYL)METHYL)BENZOTRIAZOLE& | [CAS]
122296-00-8 | [Synonyms]
benzotriazol-1-ylmethyl(trimethyl)silane
1-((TRIMETHYLSILYL)METHYL)BENZOTRIAZOLE 99%
1H-Benzotriazole, 1-[(trimethylsilyl)methyl]-
1-[(Trimethylsilyl)Methyl]-1H-1,2,3-Benzotriazole
1-((Trimethylsilyl)methyl)-1H-benzo[d][1,2,3]triazole | [Molecular Formula]
C10H15N3Si | [MDL Number]
MFCD00956443 | [MOL File]
122296-00-8.mol | [Molecular Weight]
205.33 |
| Chemical Properties | Back Directory | [Melting point ]
56-60 °C(lit.) | [Boiling point ]
300.3±25.0 °C(Predicted) | [density ]
1.06±0.1 g/cm3(Predicted) | [solubility ]
Well soluble in most organic solvents. | [form ]
solid | [pka]
1.44±0.30(Predicted) |
| Hazard Information | Back Directory | [Physical properties]
mp 55–56 °C. | [Uses]
New Benzotriazole Reagents
Reactant for:
- Alkylation reactions
- Preparation of inhibitor of p53-MDM2 complex formation
- Used as a one-carbon synthon for one-carbon homologation of carboxylic acids
| [Uses]
1-[(Trimethylsilyl)methyl]-
1H-benzotriazole is a reagent in the preparation of ketones, carboxylic acids,One-carbon Homologation of Carboxylic Acids,Synthesis of Fused Heterocycles and fused heterocycles. | [Preparation]
1-[(trimethylsilyl)methyl]-1H-benzotriazole
is readily prepared in a reaction of sodium benzotriazolide
with chloromethyltrimethylsilane. | [reaction suitability]
reaction type: C-C Bond Formation |
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