| Identification | Back Directory | [Name]
1-desoxyMethylsphinganine (M17:0) | [CAS]
1219484-98-6 | [Synonyms]
1-deoxymethylsphinganine
1-desoxymethylsphinganine
1-desoxyMethylsphinganine (M17:0)
1-DESOXYMETHYLSPHINGANINE (M17:0);1-DESOXYMETHYLSPHINGANINE | [Molecular Formula]
C17H37NO | [MOL File]
1219484-98-6.mol | [Molecular Weight]
271.48 |
| Chemical Properties | Back Directory | [Boiling point ]
395.4±15.0 °C(Predicted) | [density ]
0.873±0.06 g/cm3(Predicted) | [storage temp. ]
-20°C | [form ]
powder | [pka]
12.87±0.35(Predicted) |
| Hazard Information | Back Directory | [Uses]
1-desoxymethylsphinganine is suitable for use for testing its cytotoxic effects on primary neuron-glia cultures. It is also suitable for use as a neurotoxic agent in human CD8+ T cells. In hereditary sensory and autonomic neuropathy type I, mutations in serine palmitoyltransferase long chain base subunit 1 resulting in altered substrate specificity and accumulation of 1. | [Definition]
ChEBI: A bioactive sphingoid which is the 1-deoxymethyl derivative of sphinganine. | [Biological Activity]
1-desoxymethylsphinganine is neurotoxic towards CD8+ T cells and inhibits cytokine production. Howeverit is not cytotoxic to dopaminergic neurons. |
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| Company Name: |
Merck KGaA
|
| Tel: |
21-20338288 |
| Website: |
www.sigmaaldrich.cn |
| Company Name: |
Creative Enzymes
|
| Tel: |
1-516-855-7709 |
| Website: |
www.creative-enzymes.com |
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