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ChemicalBook--->CAS DataBase List--->1216678-68-0

1216678-68-0

1216678-68-0 Structure

1216678-68-0 Structure
IdentificationBack Directory
[Name]

Mirtazapine-D3
[CAS]

1216678-68-0
[Synonyms]

Zispin-d3
Remeron-d3
Org-3770-d3
Mirtazapine-D3
1,2,3,4,10,14b-Hexahydro-2-(methyl-d3)-pyrazino[2,1-a]pyrido[2,3-c][2]benzazepine
1,2,3,4,10,14b-Hexahydro-2-(methyl-d3)-pyrazino[2,1-α]pyrido[2,3-c][2]benzazepine
[Molecular Formula]

C17H19N3
[MDL Number]

MFCD09841051
[MOL File]

1216678-68-0.mol
[Molecular Weight]

265.353
Chemical PropertiesBack Directory
[Appearance]

Off-White to Pale Yellow Solid
[Melting point ]

105-107°C
[storage temp. ]

-20°C Freezer
[solubility ]

Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
[form ]

Solid
[color ]

White to Light Beige
Hazard InformationBack Directory
[Chemical Properties]

Off-White to Pale Yellow Solid
[Uses]

An a 2-Adrenergic blocker. An analogue of Mianserin. Antidepressant
[Uses]

An α2-Adrenergic blocker; analogue of Mianserin. Antidepressant.
[in vivo]

Mirtazapine (intraperitoneal injection; 10-50 mg/Kg; 14 days) treatment normalizes heart rate, breath rate, anxiety levels and eliminates the hopping behavior observed in MeCP2-null mice, leading to improved phenotypic score[2].

Animal Model:MeCP2 null mice[2]
Dosage:10-50 mg/Kg
Administration:Intraperitoneal injection; 10-50 mg/Kg; 14 days
Result:Restored the thickness of MeCP2-null mice somatosensory cortex, especially of layers II-III and VI.
[IC 50]

5-HT2 Receptor; 5-HT3 Receptor
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H335
[Precautionary statements ]

P261-P264-P270-P271-P301+P312-P330-P304+P340-P403+P233-P405-P501
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