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ChemicalBook--->CAS DataBase List--->1208552-99-1

1208552-99-1

1208552-99-1 Structure

1208552-99-1 Structure
IdentificationBack Directory
[Name]

(S)-2-(4-chlorophenyl)-3,3-diMethyl-N-(5-phenylthiazol-2-yl)butanaMide
[CAS]

1208552-99-1
[Synonyms]

CFMB
FFAR2 agonist 58
(S)-2-(4-chlorophenyl)-3,3-diMethyl-N-(5-phenylthiazol-2-yl)butanaMide
(2S)-2-(4-chlorophenyl)-3,3-dimethyl-N-(5-phenyl-1,3-thiazol-2-yl)butanamide
Benzeneacetamide, 4-chloro-α-(1,1-dimethylethyl)-N-(5-phenyl-2-thiazolyl)-, (αS)-
[Molecular Formula]

C21H21ClN2OS
[MDL Number]

MFCD22419579
[MOL File]

1208552-99-1.mol
[Molecular Weight]

384.92
Chemical PropertiesBack Directory
[density ]

1.241±0.06 g/cm3(Predicted)
[storage temp. ]

2-8°C
[solubility ]

DMSO: 50mg/mL
[form ]

solid
[pka]

8.81±0.50(Predicted)
[color ]

white
Hazard InformationBack Directory
[Uses]

CFMB is a full agonist of FFAR2- and FFAR3-specific with EC50 value of 0.8 μM target hFFAR2 and 0.2 μM target rFFAR2[1].
[References]

[1] Charlotte Bayer Christiansen, et al. The impact of short-chain fatty acids on GLP-1 and PYY secretion from the isolated perfused rat colon. Am J Physiol Gastrointest Liver Physiol. 2018 Jul 1;315(1):G53-G65. DOI:10.1152/ajpgi.00346.2017
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