| Identification | Back Directory | [Name]
QUINOLINE-3-CARBOXYLIC ACID | [CAS]
118803-81-9 | [Synonyms]
nuofushaxin
AKOS BBS-00005333
RARECHEM AL BO 1256
Quinoline-3-Carboxylic
mono-3-pyridinecarboxylate
Nicotinic acid Norfloxacin Injection
Norfloxacin nicotinate for injection
QUINOLINE-3-CARBOXYLIC ACID ISO 9001：2015 REACH
3-quinolinecarboxylicacid,1,4-dihydro-1-ethyl-6-fluoro-4-oxo-7-(1-piperazinyl
1-ethyl-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylicacid,pyridine-3-carboxylicaci
1-ethyl-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid,pyridine-3-carboxylic acid
3-Pyridinecarboxylic acid mono[1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylate]
3-Quinolinecarboxylic acid, 1,4-dihydro-1-ethyl-6-fluoro-4-oxo-7-(1-piperazinyl)-, mono-3-pyridinecarboxylate
3-Quinolinecarboxylic acid, 1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-, mono-3-pyridinecarboxylate
1-Ethyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid compound with nicotinic acid (1:1) | [EINECS(EC#)]
229-337-3 | [Molecular Formula]
C10H7NO2 | [MDL Number]
MFCD00006770 | [MOL File]
118803-81-9.mol | [Molecular Weight]
173.17 |
| Chemical Properties | Back Directory | [Melting point ]
277-280 °C(lit.)
| [storage temp. ]
Inert atmosphere,2-8°C | [solubility ]
DMSO (Slightly), Water (Slightly) | [form ]
White to yellow crystalline solid. |
| Hazard Information | Back Directory | [Uses]
Fluoroquinolone antibacterial agent. Derivative of norfloxacin with dramatically improved water solubility. Instantly dissociates into norfloxacin and nicotinic acid in the body therefore acting as norfloxacin. Inhibits bacterial DNA replication by interfering with an ATP-induced structural transition of DNA complexed with DNA gyrase (topoisomerase). Effective against Gram-negative bacteria; less effective against Gram-positive bacteria. | [in vivo]
Norfloxacin nicotinate (5 and/or 25 mg/L) significantly induces antioxidant enzymes activities and the mRNA levels of genes related to antioxidant enzymes and innate immune system in zebrafish larvae[1]. | [IC 50]
Quinolone |
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