| Identification | Back Directory | [Name]
N-CARBAMYL-L-GLUTAMIC ACID | [CAS]
1188-38-1 | [Synonyms]
OE 312
Carbaglu
N-Cbm-Glu-OH
carglumicaci
CargluMic Acid
ureidoglutaricacid
n-carbamylglutamate
carbamylglutamicacid
N-Carbamyl-L-glutamic
N-Carbamyl-L-glutamate
carbamino-l-glutamicacid
N-CarbaMoyl L- GlutaMate
(2S)-2-ureidoglutaric acid
N-CARBAMYL-L-GLUTAMIC ACID
N-CarbaMoyl-L-glutaMic Acid
N-CarbaMoyl-S-glutaMic Acid
(S)-2-Ureidopentanedioic acid
NCG,N-carbamyl-L-glutamic acid
Acide N-carbamoyl-L-glutamique
n-(aminocarbonyl)-l-glutamicaci
N-(AMinocarbonyl)-L-glutaMic Acid
L-Glutamic acid, N-(aminocarbonyl)-
N-CARBAMYL-L-GLUTAMIC ACID USP/EP/BP
N-carbamyl-L-glutamic acid crystalline
(2S)-2-(carbamoylamino)pentanedioic acid
(2S)-2-(aminocarbonylamino)pentanedioic acid
N-(Aminocarbonyl)-L-Glutamic Acid(Carglumic Acid) | [EINECS(EC#)]
601-569-3 | [Molecular Formula]
C6H10N2O5 | [MDL Number]
MFCD00047874 | [MOL File]
1188-38-1.mol | [Molecular Weight]
190.15 |
| Chemical Properties | Back Directory | [Melting point ]
174° | [Boiling point ]
438.1±45.0 °C(Predicted) | [density ]
1.499±0.06 g/cm3(Predicted) | [storage temp. ]
2-8°C
| [solubility ]
DMSO (Slightly), Methanol (Slightly, Sonicated) | [form ]
Solid | [pka]
3.71±0.10(Predicted) | [color ]
White to Off-White |
| Hazard Information | Back Directory | [Uses]
carbamylphosphate synthetase activator | [Uses]
N-Carbamyl-L-glutamic Acid has been shown to have protective effects against ammonia intoxication and is used in the treatment of acute hyperammonemia. | [Definition]
ChEBI: A urea that is the N-carbamoyl derivative of L-glutamic acid. An orphan drug used to treat a deficiency in the enzyme N-acetylglutamate synthase, which leads to acute hyperammonaemia. | [Biological Activity]
N-Carbamyl-L-glutamic acid (carglumic acid) is use to study its potential as a replacement therapy for N-acetylglutamate synthetase (NAGS) deficiency and to tre at hyperammonemia. |
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