| Identification | Back Directory | [Name]
A77 1726-D4 | [CAS]
1185240-22-5 | [Synonyms]
A77 1726-D4
TeriflunoMide-d4
Leflunomide-d4 Metabolite (Teriflunomide-d4)
TeriflunoMide-D4/ FlucyaMide-D4 / A77 1726-D4
N-(4-Trifluoromethylphenyl)-2-cyano-3-hydroxycrotonamide-d4, 2-Cyano-3-hydroxy-N-[4-(trifluoromethyl)phenyl]-2-beuteamide-d4, LEF-M-d4 | [Molecular Formula]
C12H9F3N2O2 | [MDL Number]
MFCD09839947 | [MOL File]
1185240-22-5.mol | [Molecular Weight]
270.207 |
| Chemical Properties | Back Directory | [Appearance]
Off-White Solid | [Melting point ]
214-217°C | [storage temp. ]
-20°C Freezer | [solubility ]
Acetonitrile (Very Slightly), DMSO (Slightly) | [form ]
Solid | [color ]
White to Off-White |
| Hazard Information | Back Directory | [Chemical Properties]
Off-White Solid | [Uses]
Labeled Leflunomide metabolite, intended for use as an internal standard for the quantification of Leflunomide metabolite by GC- or LC-mass spectrometry. | [Uses]
The active metabolite of Leflunomide, a potent disease-modifying antirheumatic drug used in the treatment of rheumatoid arthritis. LEF-M interferes with dendritic cell function | [General Description]
This stable-labeled internal standard of teriflunomide is suitable for critical quantitative applications in clinical and diagnostic testing such as therapeutic drug monitoring assays. Teriflunomide, also known as Aubagio, is the active metabolite of leflunomide, an immunosuppressive disease-modifying antirheumatic drug, used in active moderate-to-severe rheumatoid arthritis and psoriatic arthritis. |
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Sigma-Aldrich
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Merck KGaA
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