Identification | Back Directory | [Name]
Ficlatuzumab | [CAS]
1174900-84-5 | [Synonyms]
Ficlatuzumab Ficlatuzumab (anti-HGF) Research Grade Ficlatuzumab(DHD03701) |
Hazard Information | Back Directory | [Uses]
Ficlatuzumab is a monoclonal antibody (McAb) targeting human hepatocyte growth factor (HGF). Ficlatuzumab blocks the activation of the HGF/c-Met signaling pathway, and inhibits c-Met receptor-mediated cancer cell proliferation, migration, and invasion[1]. | [References]
[1] Kumar D, et al. Mitigation of Tumor-Associated Fibroblast-Facilitated Head and Neck Cancer Progression With Anti-Hepatocyte Growth Factor Antibody Ficlatuzumab. JAMA Otolaryngol Head Neck Surg. 2015 Dec;141(12):1133-9. DOI:10.1001/jamaoto.2015.2381 |
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Biolab Reagents
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Cell Sciences
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www.cellsciences.com |
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