| Identification | Back Directory | [Name]
2-Piperidinecarboxylicacid,1-hydroxy-(9CI) | [CAS]
115819-92-6 | [Synonyms]
NHP
N-Hydroxypipecolic acid
1-hydroxypiperidine-2-carboxylic acid
1-hydroxy-2-Piperidinecarboxylic acid
2-Piperidinecarboxylic acid, 1-hydroxy-
2-Piperidinecarboxylicacid,1-hydroxy-(9CI) | [Molecular Formula]
C6H11NO3 | [MDL Number]
MFCD13179004 | [MOL File]
115819-92-6.mol | [Molecular Weight]
145.16 |
| Chemical Properties | Back Directory | [Boiling point ]
336.6±31.0 °C(Predicted) | [density ]
1.359±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
2.13±0.20(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
N-Hydroxypipecolic acid (1-Hydroxy-2-piperidinecarboxylic acid), a plant metabolite and a systemic acquired resistance (SAR) regulator, orchestrates SAR establishment in concert with the immune signal salicylic acid. N-Hydroxypipecolic acid accumulates systemically in the plant foliage in response to pathogen attack. N-Hydroxypipecolic acid induces SAR to bacterial and oomycete infection[1][2][3]. | [Definition]
ChEBI: N-hydroxypipecolic acid is an N-hydroxy-alpha-amino-acid resulting from the formal N-hydroxylation of the amino group of piperidine-carboxylic acid (pipecolic acid). It is a N-hydroxy-alpha-amino-acid and a piperidinemonocarboxylic acid. It is functionally related to a pipecolic acid. | [References]
[1] Shan L, et al. Pipped at the Post: Pipecolic Acid Derivative Identified as SAR Regulator. Cell. 2018 Apr 5;173(2):286-287. DOI:10.1016/j.cell.2018.03.045
[2] ádám AL, et al. Signals of Systemic Immunity in Plants: Progress and Open Questions. Int J Mol Sci. 2018 Apr 10;19(4). pii: E1146. DOI:10.3390/ijms19041146
[3] Hartmann M, et al. N-hydroxypipecolic acid and salicylic acid: a metabolic duo for systemic acquired resistance. Curr Opin Plant Biol. 2019 Aug;50:44-57. DOI:10.1016/j.pbi.2019.02.006 |
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