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ChemicalBook--->CAS DataBase List--->113919-36-1

113919-36-1

113919-36-1 Structure

113919-36-1 Structure
IdentificationBack Directory
[Name]

2-(PHOSPHONOMETHYL)-PENTANEDIOIC ACID
[CAS]

113919-36-1
[Synonyms]

PMPA
NMDA antagonist
PMPA(NMDAantagonist)
nmda receptor antagonist
2-PHOSPHONOMETHYL-PENTANEDOIC ACID
2-(PHOSPHONOMETHYL)-PENTANEDIOIC ACID
PMPA ,2-(PHOSPHONOMETHYL)-PENTANEDIOIC ACID
4-(phosphonomethyl)piperazine-2-carboxylic Acid
4-(PHOSPHONOMETHYL)-2-PIPERAZINECARBOXYLIC ACID
2-Piperazinecarboxylicacid, 4-(phosphonomethyl)-
[Molecular Formula]

C6H13N2O5P
[MDL Number]

MFCD00940167
[MOL File]

113919-36-1.mol
[Molecular Weight]

224.15
Chemical PropertiesBack Directory
[storage temp. ]

Store at +4°C
[form ]

Powder
[Water Solubility ]

Soluble to 100 mM in water
Hazard InformationBack Directory
[Uses]

PMPA (NMDA antagonist) is a selective competitive antagonist at the NMDA receptor.
[Biological Activity]

Competitive NMDA receptor antagonist. Displays K i values of 0.84, 2.74, 3.53 and 4.16 μ M at NR2A, NR2B, NR2C and NR2D subunit-containing receptors respectively. Selective over AMPA receptors.
[IC 50]

NMDA Receptor
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202138-50-9

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