天堂网亚洲,天天操天天搞,91视频高清,菠萝蜜视频在线观看入口,美女视频性感美女视频,95丝袜美女视频国产,超高清美女视频图片

ChemicalBook--->CAS DataBase List--->1138245-21-2

1138245-21-2

1138245-21-2 Structure

1138245-21-2 Structure
IdentificationBack Directory
[Name]

Mirogabalin besylate
[CAS]

1138245-21-2
[Synonyms]

Mirogabalin besylat
Mirogabalin Besilate
Mirogabalin besylate
Mirogabalin Besylate 10928
MIROGABALIN BENZENESULFONIC ACID
Mirogabalin besylate (DS 5565 besylate)
[(1R,5S,6S)-6-(Aminomethyl)-3-ethylbicyclo[3.2.0] hept-3-en-6-yl]acetic acid benzenesulfonate
((1R,5S,6S)-6-(carboxymethyl)-3-ethylbicyclo[3.2.0]hept-3-en-6-yl)methanaminium benzenesulfonate
2-((1R,5S,6S)-6-(aminomethyl)-3-ethylbicyclo[3.2.0]hept-3-en-6-yl)acetic acid compound with benzenesulfonic acid (1:1)
[Molecular Formula]

C18H25NO5S
[MDL Number]

MFCD31631215
[MOL File]

1138245-21-2.mol
[Molecular Weight]

367.46
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[solubility ]

DMSO : 125 mg/mL (340.17 mM)
[InChI]

InChI=1/C12H19NO2.C6H6O3S/c1-2-8-3-9-5-12(7-13,6-11(14)15)10(9)4-8;7-10(8,9)6-4-2-1-3-5-6/h4,9-10H,2-3,5-7,13H2,1H3,(H,14,15);1-5H,(H,7,8,9)/t9-,10-,12-;/s3
[InChIKey]

OKJXJRVWXYRSAN-QWGAVYBYNA-N
[SMILES]

S(C1C=CC=CC=1)(O)(=O)=O.C([C@]1(C[C@@]2([H])CC(CC)=C[C@@]12[H])CN)C(=O)O |&1:11,13,20,r|
Hazard InformationBack Directory
[Description]

Mirogabalin besylate (mirogabalin, Tarlige) is a gabapentinoid therapy developed by Daiichi Sankyo, which is approved in Japan for the treatment of postherpetic neuralgia and painful diabetic peripheral neuropathy. Mirogabalin has a potent pain-modulating effect with a unique high affinity and prolonged dissociation rate for the a2delta-1 subunit of voltage-gated calcium (Ca2+) channels (VGCCs) on the dorsal root ganglion resulting in more sustained analgesia compared with traditional gabapentinoids[1].
[Side effects]

Mirogabalin has a superior adverse events (AEs) profile due to a rapid dissociation from the a2delta-2 subunit of VGCCs potentially implicated in central nervous system-specific AEs. The most common AEs for mirogabalin are dizziness (approximately 8-16%), somnolence (approximately 6-24%) and headache (approximately 6-14%), with a lower incidence of constipation, nausea, diarrhea, vomiting, edema, fatigue and weight gain[1].
[References]

[1] J Burgess. “Mirogabalin besylate in the treatment of neuropathic pain.” Drugs of today 56 2 (2020): 135–149.
1138245-21-2 suppliers list
Company Name: BEIJING SJAR TECHNOLOGY DEVELOPMENT CO., LTD.
Tel: +86-18600796368 +86-18600796368 , +86-18600796368
Website: http://www.sjar-tech.com/
Company Name: Cangzhou Kangrui Pharma Tech Co. Ltd.,
Tel: +86-18632776803 +86-13833998158 , +86-13833998158
Website: m.approvedhomemanagement.com/enterprisecertification_en_132249780.htm
Company Name: Guangzhou Tosun Pharmaceutical Ltd
Tel: +86-020-61855200-902 +8618124244216 , +8618124244216
Website: m.approvedhomemanagement.com/manufacturer/-560037/
Company Name: Wuhan JiyunZen Tech Co., Ltd.
Tel: +86-18062099985 +86-18062099985 , +86-18062099985
Website:
Company Name: ATK CHEMICAL COMPANY LIMITED
Tel: +undefined-21-51877795
Website: www.atkchemical.com
Company Name: CONIER CHEM AND PHARMA LIMITED
Tel: +8618523575427 , +8618523575427
Website: http://www.conier.com/
Company Name: Zhengzhou Alfa Chemical Co.,Ltd
Tel: +8618530059196 , +8618530059196
Website: m.approvedhomemanagement.com/manufacturer/zhengzhou-alfa-chemical-276/
Company Name: Career Henan Chemica Co
Tel: +86-0371-86658258 +8613203830695 , +8613203830695
Website: www.coreychem.com/
Company Name: HANGZHOU CLAP TECHNOLOGY CO.,LTD
Tel: 86-571-88216897,88216896 13588875226 , 13588875226
Website: www.hzclap.com/en
Company Name: Changzhou Xuanming Pharmaceutical Technology Co., Ltd.
Tel: +86-519-85525359 +86-15995072465 , +86-15995072465
Website: https://www.xuanmingchem.com
Company Name: Shandong Natural Micron Pharm Tech Co.,LTD
Tel: +86-18653895227 , +86-18653895227
Website: https://www.nmpharmtech.com/
Company Name: Finetech Industry Limited
Tel: +86-27-8746-5837 +8619945049750 , +8619945049750
Website: www.finetechnology-ind.com/
Company Name: Shenzhen Shengda Pharma Limited
Tel: 755-85269922 +8613424394241 , +8613424394241
Website: www.shengdapharm.com
Company Name: Guangzhou TongYi biochemistry technology Co.,LTD
Tel: +8613073028829 , +8613073028829
Website: http://tongyon.com/
Company Name: InvivoChem
Tel: +1-708-310-1919 +1-13798911105 , +1-13798911105
Website: https://www.invivochem.com/
Company Name: Shanghai Joiny Pharmaceutical Co.,LTD
Tel: +86-13681955282 +86-13681955282 , +86-13681955282
Website: en.joiny-pharma.com/
Company Name: Henan Aochuang Chemical Co.,Ltd.
Tel: +86-0371-63689365 +8618638391208 , +8618638391208
Website: http://www.aochuangchem.com/
Company Name: ShenZhen Trendseen Biological Technology Co.,Ltd.
Tel: 13417589054 , 13417589054
Website: m.approvedhomemanagement.com/ShowSupplierProductsList1962465/0.htm
Tags:1138245-21-2 Related Product Information

  • HomePage | Member Companies | Advertising | Contact us | Previous WebSite | MSDS | CAS Index | CAS DataBase | Privacy | Terms | About Us
  • All products displayed on this website are only for non-medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.
    According to relevant laws and regulations and the regulations of this website, units or individuals who purchase hazardous materials should obtain valid qualifications and qualification conditions.
  • Copyright © 2023 ChemicalBook All rights reserved.