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ChemicalBook--->CAS DataBase List--->1134188-71-8

1134188-71-8

1134188-71-8 Structure

1134188-71-8 Structure
IdentificationBack Directory
[Name]

OXCARBAZEPINE-D4
[CAS]

1134188-71-8
[Synonyms]

TRILEPTAL-D4
OXCARBAZEPINE-D4
10,11-DIHYDRO-10-OXO-5H-DIBENZ[B,F]AZEPINE-5-CARBOXAMIDE-D4
1,2,3,4-tetradeuterio-5-oxo-6H-benzo[b][1]benzazepine-11-carboxamide
[Molecular Formula]

C15H8D4N2O2
[MDL Number]

MFCD07369623
[MOL File]

1134188-71-8.mol
[Molecular Weight]

256.29
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[solubility ]

DMSO: soluble
[form ]

A solid
Hazard InformationBack Directory
[Description]

Oxcarbazepine-d4 is intended for use as an internal standard for the quantification of oxcarbazepine by GC- or LC-MS. Oxcarbazepine is a prodrug form of the antiepileptic compound 10,11-dihydro-10-hydroxy carbamazepine . It inhibits high-frequency repetitive firing of rat spinal cord neurons when used at a concentration of 1 μM. Oxcarbazepine protects against electroshock-induced tonic hindlimb extension (ED50s = 10-20 mg/kg), as well as seizures induced by pentylenetetrazole (PTZ; ) or picrotoxin in rodents (ED50s = 23-30 and 150-250 mg/kg, respectively). Formulations containing oxcarbazepine have been used in the treatment of epileptic seizures.
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