| Identification | Back Directory | [Name]
PEPTIDE M | [CAS]
110652-62-5 | [Synonyms]
PEPTIDE M
Peptide M, BR
ASP-THR-ASN-LEU-ALA-SER-SER-THR-ILE-ILE-LYS-GLU-GLY-ILE-ASP-LYS-THR-VAL
H-ASP-THR-ASN-LEU-ALA-SER-SER-THR-ILE-ILE-LYS-GLU-GLY-ILE-ASP-LYS-THR-VAL-OH
L-Valine, L-α-aspartyl-L-threonyl-L-asparaginyl-L-leucyl-L-alanyl-L-seryl-L-seryl-L-threonyl-L-isoleucyl-L-isoleucyl-L-lysyl-L-α-glutamylglycyl-L-isoleucyl-L-α-aspartyl-L-lysyl-L-threonyl- | [Molecular Formula]
C81H141N21O31 | [MDL Number]
MFCD00237215 | [MOL File]
110652-62-5.mol | [Molecular Weight]
1905.11 |
| Chemical Properties | Back Directory | [Boiling point ]
2138.2±65.0 °C(Predicted) | [density ]
1.310±0.06 g/cm3(Predicted) | [storage temp. ]
-15°C | [form ]
Solid | [pka]
3.32±0.10(Predicted) | [color ]
White to off-white | [Sequence]
H-Asp-Thr-Asn-Leu-Ala-Ser-Ser-Thr-Ile-Ile-Lys-Glu-Gly-Ile-Asp-Lys-Thr-Val-OH | [InChIKey]
BHGSMPANCMIOOB-VUMKDJGANA-N |
| Hazard Information | Back Directory | [Description]
Peptide M is a synthetic amino acid (18 amino acids in length which correspond to the amino acid positions 303-322 of bovine S-antigen: DTNLASSTIIKEGIDKTV), is capable of inducing experimental autoimmune uveitis in monkeys and Hartley guinea pigs as well as Lewis rats
| [Uses]
Peptide M is a synthetic amino acid (18 amino acids in length which correspond to the amino acid positions 303-322 of bovine S-antigen: DTNLASSTIIKEGIDKTV), is capable of inducing experimental autoimmune uveitis in monkeys and Hartley guinea pigs as well as Lewis rats[1]. | [in vitro]
Peptide M is immunogenic in man and provide additional support to the hypothesis that the amino acid sequence which corresponds to peptide M might be involved in uveitic conditions in man
| [References]
[1] Hirose S, et al. Lymphocyte responses to peptide M and to retinal S-antigen in uveitis patients. Jpn J Ophthalmol. 1990;34(3):298-305. PMID:1706787 |
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Musechem
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+1-800-259-7612 |
| Website: |
www.musechem.com |
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