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ChemicalBook--->CAS DataBase List--->1061747-72-5

1061747-72-5

1061747-72-5 Structure

1061747-72-5 Structure
IdentificationBack Directory
[Name]

AcetaMide, N-[2-(3,5-diMethyl-1H-pyrazol-1-yl)-6-[6-(4-Methoxy-1-piperidinyl)-2-pyridinyl]-4-pyriMidinyl]-
[CAS]

1061747-72-5
[Synonyms]

TC-G 1004
TCG 1004,TC G 1004
N-[2-(3,5-dimethylpyrazol-1-yl)-6-[6-(4-methoxypiperidin-1-yl)pyridin-2-yl]pyrimidin-4-yl]acetamide
N-[2-(3,5-Dimethyl-1H-pyrazol-1-yl)-6-[6-(4-methoxy-1-piperidinyl)-2-pyridinyl]-4-pyrimidinyl]acetamide
AcetaMide, N-[2-(3,5-diMethyl-1H-pyrazol-1-yl)-6-[6-(4-Methoxy-1-piperidinyl)-2-pyridinyl]-4-pyriMidinyl]-
[Molecular Formula]

C22H27N7O2
[MOL File]

1061747-72-5.mol
[Molecular Weight]

421.5
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[solubility ]

Soluble to 100 mM in 1eq. HCl and to 100 mM in DMSO
[form ]

Powder
[color ]

Yellow to orange
Hazard InformationBack Directory
[Uses]

TC-G 1004 is a small molecule agonist of the A2A G-protein coupled receptor.
[in vivo]

TC-G 1004 (compound 16j, 3 mg/kg) displays good in vivo oral activity in rat models for Parkinson’s disease and were advanced to preclinical development[1].
TC-G 1004 (compound 16j) dose-dependently potentiates L-dopa induced rotations with an MED of 3 mg/kg when dosed orally[1].

[storage]

Store at -20°C
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