| Identification | Back Directory | [Name]
8(R)-HYDROXY-(5Z,9E,11Z,14Z)-EICOSATETRAENOIC ACID | [CAS]
105500-09-2 | [Synonyms]
8[R]-HETE
NLUNAYAEIJYXRB-GTYUHVKWSA-N
8(R)-hydroxy-(5Z,9E,11Z,14Z)-*eicosatetraenoic ac
8(R)-HYDROXY-(5Z,9E,11Z,14Z)-EICOSATETRAENOIC ACID
5,9,11,14-Eicosatetraenoic acid, 8-hydroxy-, (5Z,8R,9E,11Z,14Z)- | [EINECS(EC#)]
200-578-6 | [Molecular Formula]
C20H32O3 | [MDL Number]
MFCD00065823 | [MOL File]
105500-09-2.mol | [Molecular Weight]
320.47 |
| Chemical Properties | Back Directory | [Boiling point ]
471.1±45.0 °C(Predicted) | [density ]
0.984±0.06 g/cm3(Predicted) | [storage temp. ]
−20°C | [solubility ]
0.1 M Na2CO3: 2 mg/ml; DMF: Miscible; DMSO: Miscible; Ethanol: Miscible; PBS pH 7.2: 0.8 mg/ml | [pka]
4.75±0.10(Predicted) |
| Hazard Information | Back Directory | [Uses]
8(R)-HETE is biosynthesized by lipoxygenation of arachidonic acid in marine invertebrates such as gorgonian corals and starfish. Stereochemical assignment of the (R) enantiomer is based on comparison of chiral HPLC retention times to published results. | [Definition]
ChEBI: A HETE having an (8R)-hydroxy group and (5Z)-, (9E)-, (11Z)- and (14Z)-double bonds. | [References]
[1] Meijer, et al. Stereospecific induction of starfish oocyte maturation by (8R)-hydroxyeicosatetraenoic acid. J. Biol. Chem. 261(36), 17040-17047 (1986). |
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