Identification | Back Directory | [Name]
[1-phosphono-2-(pyridin-2-ylamino)ethyl]phosphonic acid | [CAS]
105462-22-4 | [Synonyms]
NE11808 NE-11808 NE 11808 [1-phosphono-2-(pyridin-2-ylamino)ethyl]phosphonic acid | [Molecular Formula]
C7H12N2O6P2 | [MOL File]
105462-22-4.mol | [Molecular Weight]
282.128 |
Hazard Information | Back Directory | [Description]
NE11808 is FPP synthase inhibitor. | [Uses]
NE11808 is a potent antiresorptive bisphosphonate that inhibits osteoclast prenylation and effectively inhibits protein prenylation in osteoclasts and suppresses labeling of dye-front end compounds. | [References]
[1] Structure-activity relationships for inhibition of farnesyl diphosphate synthase in vitro and inhibition of bone resorption in vivo by nitrogen-containing bisphosphonates PMID:11160603 |
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