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ChemicalBook--->CAS DataBase List--->1052207-59-6

1052207-59-6

1052207-59-6 Structure

1052207-59-6 Structure
IdentificationBack Directory
[Name]

BocNH-PEG8-CH2CH2NH2
[CAS]

1052207-59-6
[Synonyms]

BocNH-PEG8-CH2CH2NH2
tert-Butyl (26-amino-3,6,9,12,15,18,21,24-octaoxahexacosyl)carbamate
5,8,11,14,17,20,23,26-Octaoxa-2-azaoctacosanoic acid, 28-amino-, 1,1-dimethylethyl ester
Tert-butyl N-[2-[2-[2-[2-[2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl]carbamate
[Molecular Formula]

C23H48N2O10
[MDL Number]

MFCD31656919
[MOL File]

1052207-59-6.mol
[Molecular Weight]

512.63
Chemical PropertiesBack Directory
[Boiling point ]

579.4±50.0 °C(Predicted)
[density ]

1.078±0.06 g/cm3(Predicted)
[solubility ]

Soluble in Water, DMSO, DCM, DMF
[form ]

Liquid
[pka]

12.23±0.46(Predicted)
[color ]

Colorless to light yellow
Hazard InformationBack Directory
[Uses]

Boc-NH-PEG8-CH2CH2NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
[IC 50]

PEGs
[References]

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
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