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ChemicalBook--->CAS DataBase List--->105114-63-4

105114-63-4

105114-63-4 Structure

105114-63-4 Structure
IdentificationBack Directory
[Name]

ZK 112993
[CAS]

105114-63-4
[Synonyms]

ZK 112993
11β-(4-Acetylphenyl)-17β-hydroxy-17-(1-propynyl)estra-4,9-dien-3-one
[Molecular Formula]

C29H32O3
[MDL Number]

MFCD32200351
[MOL File]

105114-63-4.mol
[Molecular Weight]

428.563
Hazard InformationBack Directory
[Uses]

ZK112993 is a potent progesterone receptor (PR) antagonist. ZK112993 significantly inhibits the growth of T61 human tumors in nude mice[1].
[References]

[1] C A Sartorius, et al. Antagonist-occupied human progesterone receptors bound to DNA are functionally switched to transcriptional agonists by cAMP. J Biol Chem. 1993 May 5;268(13):9262-6. PMID:8387487
[2] Claudia Lanari, et al.? Antiprogestins in breast cancer treatment: are we ready? Endocr Relat Cancer. 2012 May 3;19(3):R35-50. DOI:10.1530/ERC-11-0378
105114-63-4 suppliers list
Company Name: TargetMol Chemicals Inc.
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Website: www.targetmol.com/
Company Name: TargetMol Chemicals Inc.
Tel: +8613564774135 , +8613564774135
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Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Website: https://www.targetmol.cn/
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