| Identification | Back Directory | [Name]
Glutaroyl carnitine | [CAS]
102636-82-8 | [Synonyms]
Glutaroyl carnitine
DL-Glutaryl Carnitine
(L)-Glutaryl Carnitine
Glutaroyl N-(methyl-D3)-carnitine
L-Glutaryl Carnitine
DISCONTINUED. Please see G597605
(2R)-3-Carboxy-2-(4-carboxy-1-oxobutoxy)-N,N,N-triMethyl-1-propanaMiniuM Inner Salt | [Molecular Formula]
C12H21NO6 | [MDL Number]
MFCD16036250 | [MOL File]
102636-82-8.mol |
| Chemical Properties | Back Directory | [storage temp. ]
2-8°C | [solubility ]
DMSO, Methanol, Water | [form ]
Gel | [color ]
Clear Colourless | [optical activity]
[α]/D -20±2°, c = 1 in H2O | [Stability:]
Very Hygroscopic |
| Hazard Information | Back Directory | [Chemical Properties]
Clear Thick Gel | [Uses]
A metabolite of L-Carnitine (C184110). | [Definition]
ChEBI: O-glutaroyl-L-carnitine is an O-acyl-L-carnitine in which the acyl group is specified as glutaroyl. It has a role as a human metabolite. It is functionally related to a glutaric acid. | [Biochem/physiol Actions]
Increased formation and excretion of glutarylcarnitin results from a glutaryl-CoA dehydrogenase deficiency, an inborn error of lysine and tryptophan metabolism. Secondary carnitine depletion due to increased formation and urinary excretion of glutarylcarnitine is suggested to play an important role in the neuropathogenesis of glutaryl-CoA dehydrogenase deficiency, inducing excitotoxic neuronal damage and mitochondrial dysfunction. | [IC 50]
Human Endogenous Metabolite | [storage]
Store at -20°C |
|
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