| Identification | Back Directory | [Name]
2-Benzylpropionic acid | [CAS]
1009-67-2 | [Synonyms]
2-Benzylpropionicacid
2-Benzylpropanoic acid
α-methylhydrocinnamic acid
a-Methylhydrocinnamic acid
a-Methyldihydrocinnamic acid
α-Methylbenzenepropionic acid
alfa-Methylhydrocinnamic acid
alpha-Methylhydrocinnamic acid
2-Methyl-3-phenylpropionic acid
1-METHYL-2-PHENYLPROPIONIC ACID
2-Methyl-3-phenylpropanoic acid
Propanoic acid, 2-(phenylmethyl)-
alpha-Methylhydrocinnamic acid,98%
alpha-MethylhydrocinnaMic acid 98%
(+/-)-a-Methylbenzenepropanoic acid | [EINECS(EC#)]
201-982-5 | [Molecular Formula]
C10H12O2 | [MDL Number]
MFCD00192301 | [MOL File]
1009-67-2.mol | [Molecular Weight]
164.2 |
| Chemical Properties | Back Directory | [Appearance]
white to light yellow crystalline powder or | [Melting point ]
39-41 °C(lit.)
| [Boiling point ]
167-168 °C23 mm Hg(lit.)
| [density ]
1.065 g/mL at 25 °C(lit.)
| [refractive index ]
1.5155 (estimate) | [Fp ]
>230 °F
| [form ]
Crystalline Powder or Crystals | [pka]
4.69±0.10(Predicted) | [color ]
White to light yellow | [InChI]
InChI=1S/C10H12O2/c1-8(10(11)12)7-9-5-3-2-4-6-9/h2-6,8H,7H2,1H3,(H,11,12) | [InChIKey]
MCIIDRLDHRQKPH-UHFFFAOYSA-N | [SMILES]
C1(=CC=CC=C1)CC(C)C(=O)O |
| Hazard Information | Back Directory | [Chemical Properties]
white to light yellow crystalline powder or | [Uses]
α-Methylhydrocinnamic acid is suitable for use in the comparative study to investigate the γ-globin inducibility of short-chain fatty acid derivatives (SCFADs) in mice. 1 It may be used as a histone deacetylase (HDAC) inhibitor in the comparative study to investigate the EGFP-induction potency of a number of HDAC inhibitors. 2 It may be used in the study to investigate the selectivity of the sensor based on imprinted poly( o -phenylenediamine) (iPoPD). | [General Description]
α-Methylhydrocinnamic acid (2-methyl-3-phenylpropionic acid, 2-benzylpropionic acid) is a cinnamic acid derivative. Its synthesis by the asymmetric hydrogenation of α-methylcinnamic acid has been reported. α-Methylhydrocinnamic acid, a short chain fatty acid derivative (SCFAD), has been reported to correct the cystic fibrosis transmembrane conductance regulator (ΔF508-CFTR) defect. Conformational studies of 2-methyl-3-phenylpropionic acid has been investigated by NMR spectroscopy. The enantiomers of 2-benzylpropionic acid has been reported to be synthesized using a lipase-catalyzed resolution. (S) (+)-2-methyl-3-phenylpropionic acid participates in the synthesis of optically active (R)-5-methyl-6-phenylhexanoyl azide. L-2-Methyl-3.phenylpropionic acid has been reported to be an inhibitor of carboxypeptidase A. Polymer-supported “Evans” oxazolidinone mediated solid phase asymmetric has been employed in the synthesis of (S)-2-methyl-3-phenylpropionic acid. |
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