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ChemicalBook--->CAS DataBase List--->1003736-23-9

1003736-23-9

1003736-23-9 Structure

1003736-23-9 Structure
IdentificationBack Directory
[Name]

Photoregulin1
[CAS]

1003736-23-9
[Synonyms]

Photoregulin1
[Molecular Formula]

C21H23N3O2S
[MOL File]

1003736-23-9.mol
[Molecular Weight]

381.49
Chemical PropertiesBack Directory
[density ]

1.37±0.1 g/cm3(Predicted)
[pka]

14.29±0.70(Predicted)
Hazard InformationBack Directory
[Description]

Photoregulin1 is a novel modulator of Nr2e3, slowing the progression of photoreceptor degeneration in two common mouse models of autosomal dominant RP, the RhoP23H and the Pde6brd1 mutations.
[Uses]

Photoregulin1 is a compound with the potential to inhibit retinitis pigmentosa that modulates gene expression in retinal cells and slows the degeneration of photoreceptors in a mouse model.
[References]

[1] Potential of Small Molecule-Mediated Reprogramming of Rod Photoreceptors to Treat Retinitis Pigmentosa DOI:10.1167/iovs.16-20177
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